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Pemberton's sign

Etiology: - superior vena cava syndrome due to obstruction of the thoracic inlet - goiter with enlarged thyroid compressing subclavian vein & jugular vein [1] Clinical manifestations: - reversible facial congestion after elevation of both arms * images & video [1]

General

sign/symptom

References

  1. Abu-Shama Y, Cuny T. Pemberton's Sign in a Patient with a Goiter. N Engl J Med 2018; 378:e31. May 31, 2018 PMID: 29847764 https://www.nejm.org/doi/full/10.1056/NEJMicm1712263
  2. Medical Knowledge Self Assessment Program (MKSAP) 18, American College of Physicians, Philadelphia 2018